Since the 16th century, the Monastery, like many others, had functioned as an idiorhythmic community. In July 1813, a declaration by its Great Assembly announced the decision of the Karakallos Monastery to readopt the cenobitic system of monastic life, with the hieromonk Nektarios from the Ascension cell as the new Abbot. The transition to the cenobitic mode was consolidated by the patriarch Kyrillos VI's sigillion issued in the same year.
